Endocrine Abstracts

Cinacalcet increases sensitivity of the calcium sensing-receptor, currently licenced for treatment of refractory secondary hyperparathyroidism in patients with end-stage renal disease. It decreases parathyroid hormone, calcium and phosphorus levels. There is no clinical data for the use of Cinacalcet in pregnancy. Hyperparathyroidism is rare during pregnancy, mainly presenting early, when surgery is safely performed. Here we report a patient presenting with a MEN1-associated p...

Klinefelter’s syndrome is the most common cause of primary testicular failure, resulting in impairment of both spermatogenesis and testosterone production. It is a chromosomal disorder characterized testosterone deficiency with elevated gonadotropin plasma levels and the treatment involves supplementing testosterone. In Klinefelter’s syndrome there is an increase of certain systemic diseases including venous thromboembolism. It is nevertheless more frequent than in a...

Introduction: Thyrotoxicosis is one of the common referrals to the endocrine clinic. Management of the thyrotoxicosis depends on establishing the correct aetiology. The aim of the audit was to compare the management of patients with thyrotoxicosis against the guidelines proposed by the Royal College of Physicians.Methods: One hundred and two consecutive patients referred to outpatient endocrine unit in a University Hospital over 6 months were included. D...